Do neurometabolite levels predict reading ability?

Via Dorothy Bishop (@deevybee), who has taken advantage of the new Pub Med Commons system to comment on the following paper:

Pugh, K. R., Frost, S. J., Rothman, D. L., Hoeft, F., Del Tufo, S. N., Mason, G. F., . . . Fulbright, R. K. (2014). Glutamate and choline levels predict individual differences in reading ability in emergent readers. Journal of Neuroscience, 34(11), 4082-4089. doi: 10.1523/jneurosci.3907-13.2014

Pugh et al report correlations between levels of neurometabolites glutamate and choline (measured by magnetic resonance spectroscopy) and reading ability in children. However, the central result that they report is based on data that are not corrected for age, which ranges from 6 to 10 years, and there are other aspects of the results that are not reported in sufficient detail for proper evaluation.

Full comment (lots of detail!)



About Andrew D Wilson

I am a Senior Lecturer in Psychology at Leeds Beckett University. My research is in perception, action and embodied cognition.
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